The building that houses the War Museum of Thessaloniki is located in the wider area of the camp of Pedio tou Areos , at the headquarters of the 3rd Army Corps. The building was designed by Italian architect Vitaliano Poselli (1838-1918) in the early 20th century and was originally used by the Ottoman Army. .
When Thessaloniki was liberated in 1912 by the Greek Army, it came under its ownership and military units were established there. After a period of being obsolete, the political and military leadership of the country decided to house here the War Museum of the city as a Branch of the War Museum of Athens.
Renovation and reconstruction works began in 1993. Upon completion, the Museum opened its gates to the public in 2000.